What Does the Research Say About NAD+?
A recent study published in Cell Metabolism in 2019 examined the role of NAD+ boosters. The researchers found links between NAD+ levels and obesity; because key enzymes in NAD+ signaling pathways are known to prevent fatty liver diseases like fat accumulation and insulin resistance. In fact, an animal study found that when mice were treated with NAD+, they were able to treat and prevent obesity, improve blood glucose levels and mitochondrial function – all essential biomarkers of health and longevity.
One of the key hallmarks of aging is muscular atrophy and inflammation. A 2013 study published in the journal Cell found that prior to treating old mice with NAD+ precursors, they experienced ‘dramatically improved’ muscle function. This happened because NAD+ plays a role in mitochondrial function, reducing inflammation and helps ATP production, for exercise performance.
NAD+ has neuroprotective effects, meaning that it protects your brain and supports cognitive performance. Studies show NAD+ therapy can delay the effects of neurodegenerative diseases like Alzheimer’s, and improves cognition and neural plasticity. This can help boost memory recall, mental clarity, energy levels, and attention span. It does this because NAD+ powers our brain cells, without enough, your brain can’t function optimally.
Another aspect of cognitive health is your mood. NAD+ is a precursor to various metabolic pathways including serotonin, melatonin, dopamine, noradrenaline, and kynurenine – to name a few. You’ve likely heard of some of these, like serotonin, due to its connection with your mood. Without NAD+, you can’t produce these important hormones and metabolites, resulting in deficiency or dysfunction. Serotonin deficiency is linked to many conditions like depression, anxiety, obsessive-compulsive disorder, brain fog, and obesity. Ensuring your NAD+ levels are high will allow the rest of the associated functions to work properly so that you can feel your best.
NAD+ has anti-inflammatory properties. An animal study found that when treated with NAD+ precursors, inflammatory markers decreased. Inflammation is known to be at the root of all disease and illness, ranging from obesity to acne – inflammation is involved. Reducing levels of inflammation in the body is associated with improved general and cognitive health, as well as improved mood, energy levels and a reduced risk of all-cause mortality. Want to know one of the best ways to reduce inflammation? NAD+.